https://public.tableau.com/app/profile/bireme/viz/OzonetherapyfortreatmentofCOVID-19/evidence-map

This evidence map presents a graphical synthesis of clinical studies on the application of Ozone Therapy in COVID-19 cases. From an extensive literature search, 13 clinical studies were included in the map and categorized by type of intervention and by outcomes. The studies evaluated the effect of 4 types of intervention with ozone therapy: major autohemotherapy, minor autohemotherapy, rectal insufflation and ozonized saline solution; for 6 groups of COVID-19-related outcomes: clinical improvement; hospital internment; inflammatory, thromboembolic, infectious or metabolic markers; radiological aspects; viral infection; and adverse events.